Making sense of the hairball
by Natasa Przulj
Network topology contains biological data. Topological structures are preserved across species
Wrote software for network alignment:
basic approach is seed and extend.
MI allows nodes to have similarity values, which provide additional information for the alignment.
degree of node and connection pattern defines ‘graphlets’
Graph crunch software.
See also Isorank, by Bonnie Berger’s lab.