Janet Thornton- evolution of enzyme mechanisms and functional diversity

Grand vision- an arrow showing the pathway for bioinformatics:
Dictionary– the parts (genes,proteins,etc)
Thesaurus– the interactions
Circuit diagram– the biological networks
Atlas– where (and when) it happetns.

We are only at the thesaurus stage

Data doubles every 5 months

Comparing, clustering, evolution of bio chemistry.

Most enzyme evolution (90%) is within the same enzyme class, adopting to either a new substrate or new product.


Posted on July 18, 2011, in Uncategorized and tagged . Bookmark the permalink. Leave a comment.

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