rates of HIV evolution

Prabhav suggested comparing rates of viral evolution within patients to those within a transmission cluster.

We could measure/compare rates of adoptation to treatment to rates of adoptation to a new host.

The confound is that we identify the transmission clusters via genetic distance. It would be easier if we had a known transmission chain.

Alternately, EuResist does have ~6000 cases with two samples taken under one treatment. We could compare rates here with rates after a treatment change.

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Posted on October 26, 2011, in evolution and tagged , , . Bookmark the permalink. Leave a comment.

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